What you will own at Wildtype:

• Produce our current scaffolds with novel cell adhesion, proliferation, and differentiation cues
• Tissue engineer muscle, fat, and connective tissue, including cell seeding, scaffold stimulation, and harvest to packaging
• Analyze experimental samples by light microscopy, fluorescence-based immunoassays, colorimetric assays, histology, and mechanical assays
• Carry out experiments with the guidance of our scientific leadership maintain accurate notes, present data, be engaged in scaffold rational redesign and experimental planning
• Acquire new skills and integrate new technologies

What we’ll teach you:

• How to apply your tissue engineering skills in the context of next-generation sustainable food production
• Scale up basic tissue engineering techniques to unprecedented volumes
• How to continue growing as a scientist with outside-the-box thinking, creative experimental design, execution, and analysis
• New techniques such as hybrid scaffold fabrication, functional assays, advanced microscopy, molecular biology, and screening methodologies

What you bring to Wildtype:

• 2+ years of mammalian cell culture experience or 1+ years of stem cell culture experience
• Exceptional aseptic technique with a great understanding of the fundamentals of cell culture in 3D scaffolds
• Experience preparing analytical reagents and dilutions
• Experience with molecular biology is a plus
• Experience with mechanical engineering, CAD, 3D printing, nanofiber creation is also a plus
• Comfortable taking notes, writing reports, and performing laboratory-related arithmetic
• Capable of overcoming obstacles/difficulties with a positive attitude; enjoys challenges; proven ability to see goals through to the end
• A hunger for learning, growth, and being part of a fast-moving, dynamic team
• Strong attention to detail and excellent organization skills
• Able to learn quickly and excel in a fast-paced work environment
• Self-starter, willing to take initiative to accomplish key tasks

Impact Plan:

• Within 1 month you’ll have carried out your first experiment on your own, with the support of your scientific mentor. We’ll rely on you to prepare scaffolds and other experimental reagents without supervision. You will have performed a few advanced analyses (including taste tests) on the samples you have produced. You will have defined your professional development goals for the next twelve months.
• Within 3 months you will have mastered basic tissue engineering lab techniques within Wildtype’s unique context. You will be independently carrying out routine activities such as cell culture, cell seeding, differentiation, and sample analyses without supervision. You will have contributed to the design of several experiments.
• Within 6 months your tissue engineering skills will have developed to the point where you can independently train a new hire on Wildtype’s entire product production process. Your work will be organized effectively to achieve tasks on time at a high level of quality. You will have executed your first independently designed experiment with controls, and presented your findings at a company-wide research meeting.
• Within 12 months you’ll be managing and carrying out multiple experiments simultaneously. You will be able to articulate how your work directly impacts the company’s milestones. You will routinely take the initiative to research topics independently and volunteer new ideas or approaches.

Your work at Wildtype

• Flexible schedule, up to 10 hours per month

• Lead grocery shopping and preparation (including making seasoned sushi rice) for sushi, poke, smoked salmon, and cured salmon dishes (such as ceviche) for tastings with chefs, restaurateurs, investors and partners

• Lead grocery shopping and preparation, as well as assist with food styling, for marketing-oriented photo shoots and events

• Opportunities for occasional travel (not required)

What you bring to the table

• 2+ years making sushi in an upscale sushi restaurant

• Ability to wow diners with preparation and plating techniques

• Ability to source and prepare ingredients in advance of tastings

• Ability to speak to the story behind our product and the dishes you’ve prepared

• Highly skilled, highly dependable, highly reliable

What you will own at Wildtype

• Design and validate novel downstream processes and systems to achieve large-scale, high-viability cell harvests for subsequent integration with Wildtype’s industry-leading bioscaffolds

• Oversee the manufacture and integration of various downstream process systems within Wildtype’s cell cultivation facility

• Troubleshoot and optimize key process parameters (e.g., flow rates, mixing dynamics, and viability optimization strategies) to improve production efficiency

• Work with our Process Development, Scaling, and Tissue Engineering teams to create novel large scale cell-scaffold integration systems

• Communicate and negotiate with vendors, contractors, and other outside parties

• Acquire new skills and integrate new technologies

What we’ll teach you

• How to apply your bioprocess and mechanical engineering skills to the context of our unique cultivated seafood manufacturing systems

• How to work with a fast-moving, interdisciplinary team working at the leading edge of several fields

What you bring to Wildtype

• MS or PhD in Bioprocess Engineering, Mechanical Engineering, Fluidics, or Food Engineering with 3+ years of process development experience

• Hands-on experience in designing downstream processes and operating bioreactors

• A creative and fearless approach to reinventing downstream systems for the purpose of cultivated seafood production; the types of systems you will build are the first of their kind!

• Ability to perform mass, flow, and thermal calculations and analyses on proposed process changes to accurately predict resultant changes

• Working knowledge of process engineering software packages, SolidWorks, CAD, or AutoCAD preferred

• Ability to work independently in experiment planning, design, execution, optimization, data analysis, interpretation, and communication

• Excellent organizational, communication skills and a track record of effective collaboration in complex projects

• Mission-driven, creative, and entrepreneurial

Impact Plan

• Within 1 month you will have adapted your experience in process development to Wildtype’s unique context. You will have set your professional development goals for the next twelve months.

• Within 3 months you will have assumed responsibility for Wildtype’s downstream process development, including the design, validation, operation, and maintenance of the company’s downstream processes. You will have written and operationalized standard procedures consistent with good manufacturing practices for cell harvest and delivery to our cell-scaffold integration systems. You will regularly design and test new equipment as Wildtype continues to scale its production capacity.

• Within 6 months your efforts on R&D over the past six months will have also yielded significant improvements to Wildtype’s production efficiencies. Your leadership responsibilities will expand as our production team grows. You will have trained several new hires and built a high-performing team. You will have also defined hiring plans for the next stage of Wildtype’s growth into 2022 and 2023. You will be working closely with our leadership team to set production goals and manage output for Wildtype’s pilot plant.

• Within 12 months you will be overseeing the downstream processing of cells in the world’s first pilot-scale facility for cultivated seafood. You will be working closely with our facilities and lab managers to meet production and R&D demands. You will also be playing a key role in selecting and designing a site for Wildtype’s next production facility.

What you will own at Wildtype

• Work with our process development team to scale-up bench-scale processes for novel cell strains & improve cell manufacturing processes

• Troubleshoot and optimize key process parameters (e.g., feeding strategies, culture mixing dynamics, sparging) to improve production efficiency

• Tech-transfer of large scale upstream processes to production team

• Monitor processes and prepare samples for downstream analyses

• Maintain accurate experimental records

• Design and implement processes for culturing novel cell lines

• Assist in company efforts to scale up cell culture

What you bring to the table

• MS or PhD in Bioprocess Engineering, Cell/Molecular Biology, Biochemistry, Chemical, or Biochemical Engineering with 3+ years of process development experience; prior experience in biotechnology/bio-pharmaceutical industry is a plus

• Experience with resolving engineering issues, particularly involving process scale up

• Ability to establish scaled down models based upon large scale run data

• Experience with the design of mammalian or insect cell culture processes, and the operation of large scale bioreactors

• Ability to work independently with respect to experiment planning, design, execution, optimization, data analysis, interpretation, and communication

• Excellent organizational, communication skills and a track record of effective collaboration in complex projects

• Mission-driven, creative, and entrepreneurial

What we’ll teach you

• How to apply your experience in large-scale cell culture to the production of next-generation seafood

Impact plan

• Within 1 month you will have adapted your experience in process development to Wildtype’s unique context. You will have set your professional development goals for the next twelve months.

• Within 3 months you will have assumed responsibility within Wildtype’s process development / scaling team including process validation, operation, and maintenance of the company’s fleet of bioreactors. You will have identified key performance indicators from bench scale runs that will facilitate an increase in scale. You will also coordinate technology transfers to Wildtype’s production team.

• Within 6 months your efforts on R&D over the past six months will have also yielded significant improvements to Wildtype’s scale-up processes. Your leadership responsibilities will expand as our process development / scaling team grows. You will have trained new hires and transferred processes to the production team.

• Within 12 months you will have successfully orchestrated the scale-up of multiple marine cell lines. You will have developed workflows for the improvement of key culture parameters in novel cell lines developed by our Cell Line Development team. At this stage, you will also be interfacing with the Media and Production teams to optimize the process for large scale cell propagation and production. You will also play an integral role in defining the requirements for future production plants.